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But if you dont have enough B12, those processes slow down and you feel tired and exhausted

Zhao WJ, Hang BJ, Zhu XC, Wang R, Shen MJ, Huang L, Xu ZN (2016) Improving the productivity of S-adenosyl-L-methionine by metabolic engineering in an industrial Saccharomyces cerevisiae strain

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A patient who is plateaued because they are on a sub-therapeutic GLP-1 dose, where dose optimisation is the actual answer

Theyre also helpful for people who dont get enough B12 from their diet (spoiler: often vegetarians and vegans) and for people whose guts cant break down and absorb the vitamin