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Even the lowest doses in B12 supplements are many times the recommended dietary allowance
(2) treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo GSH synthesis for 2448 h
Though more human studies are needed, early findings are promising
High activity of NNMT is also correlated with lower levels of glucose transporter 4 (GLUT4), which is vital for glucose uptake from the bloodstream into fat and muscle cells
doi:10.1177/1933719117711262
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