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"Age-dependent decrease of carnitine content in muscle of mice and humans." National Library of Medicine

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Conclusion Understanding changes in clinical characteristics and treatment patterns over time among new users of SGLT2i or GLP-1 RA in the US as described in this observational study is important to inform and contextualize future studies assessing cardiorenal outcomes for these and additional treatments, including finerenone, for individuals with CKD and type 2 diabetes