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Preclinical models of IBD demonstrate that paroxetine administration significantly alleviates intestinal inflammation by downregulating a broad cascade of pro-inflammatory markers, including TNF-, IL-1, IL-6, IL-17a, and IL-23a, while simultaneously reducing the expression of anti-TNF--resistance biomarkers like Osm and Osmr (Tang et al., 2015

In scientific studies, silymarin acts both choleretically (stimulates bile production in the liver) and chokinetically (supports gallbladder contraction and bile flow)

Combining with other recovery or regenerative protocols (e.g., nutrition, rest, physical therapy) to maximize effect

Ferroptosis: An Iron-dependent form of nonapoptotic cell death

Senolytic therapies targeting anti-apoptotic pathways can eliminate senescent cells and enhance chemoradiotherapy efficacy of cancer 10,32