the importance of glutathione in human disease Glutathione Metabolism and Its Implications

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Pathological alterations in gut microbiota induce the increased production of toxic metabolites and reduced production of beneficial compounds like short-chain fatty acids

The efficacy of tumor immunotherapy was found to be enhanced by a regulatory mechanism where interaction between MFN-2 and SERCA-2 proteins present at the mitochondrion-ER site helps to modulate the function and metabolism of cytotoxic T-lymphocytes, thereby promoting MFN-2 expression levels [430]