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Inter J Food Sci Nutr 73:10471056
There was no apparent effect of renal impairment, hepatic impairment or upper GI disease on the PK and tolerability of orally administered semaglutide, suggesting that dose adjustment is not necessary in these special populations [11, 31,32,33]
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The patch typically contains the active GLP-1 analogue within a reservoir or matrix system, alongside penetration enhancers that facilitate drug passage through the stratum corneum (the skin's outer protective layer)
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