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Certain individuals should not receive glutathione injections or should do so only under careful medical supervision: Pregnant or nursing women (insufficient safety data in this population) Individuals with known allergies to sulfur-containing compounds Patients currently undergoing chemotherapy without oncologist clearance People with severe asthma (sulfite sensitivity can trigger bronchospasm in rare cases) Patients with significant kidney disease A thorough medical consultation before treatment helps identify any contraindications and ensures patient safety