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Sphingosine-1-phosphate signal transducer and activator of transcription 3 signaling pathway contributes to baicalein-mediated inhibition of dextran sulfate sodium-induced experimental colitis in mice

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After 12 weeks: people who received 140 mg of Repatha every 2 weeks with a statin had their LDL levels lowered by 63% people who received a placebo every 2 weeks had their LDL levels increased by 8% people who received 420 mg of Repatha once a month had their LDL levels reduced by 59% people who received a placebo once a month had their LDL levels increased by 4% Repatha for reducing the risk of heart attack, stroke, or the need for certain heart surgeries in adults with heart disease Repatha is FDA approved to reduce the risk of heart attack or stroke and to reduce the need for certain heart surgeries in adults with heart disease

& Baeuerle, P