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In vitro assays using BaF-BO3 cells transfected with the hGH receptor confirmed that AOD9604 does not compete for the hGH receptor and does not induce cell proliferation unlike intact hGH establishing that it operates via a novel mechanism distinct from traditional hGH-stimulated pathways

Platelet-rich plasma (PRP) therapy, for example, provides a mixture of autologous growth factors and cytokines and has more established clinical evidence for certain applications

[65] In some severe cases of anemia, a blood transfusion may be needed to resolve haematological effects

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