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This tolerability profile raises the question of whether patients could transition directly from injectable incretin therapy to higher doses of orforglipron, potentially minimizing the dose-escalation period required to reach equipotent dosing
Diarrhea For cagrilinitide and semagludide the risk of diarrhea was increasing for the lowest dosages at a faster rate, followed by a tendency to plateauing at highest dosages
V., Osna, N
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The starting dose (0.25 mg) is primarily for adjustment, not weight loss
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