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China Patent Application CN105685226 (A) Yin H, Ma Y, Deng Y, Xu Z, Liu J, Zhao J, Dong J, Yu J, Chang Z (2016) Genome shuffling of Saccharomyces cerevisiae for enhanced glutathione yield and relative gene expression analysis using fluorescent quantitation reverse transcription polymerase chain reaction

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In vitro experiments confirmed that SPY1 overexpression significantly activated the GCH1/BH4 signaling pathway in NSC-34 cells transfected with the human SOD1 G93A gene