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2 Next-generation redox-adaptive nanoplatforms: insights from recent breakthrough studies Recent work has rapidly advanced organelle-targeted, microenvironment-activated nanomedicines that directly intersect with glutathione (GSH)-responsive sensing and therapeutics Table 1

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Moreover, both dietary intake and GABA- producing microbes are additional sources of GABA that may modify the islet milieu but not be reflected by circulating concentrations (127, 163)

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