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Results Anti-nitrative effect of trisulfides as an introductory part of the study Given the potent anti-oxidative functions of GSSSG and LASSS, the first set of experiments was designed to examine if these trisulfides have potential to prevent peroxynitrite-induced nitration-dysfunction of HGF by ECL-Western blotting (see Figure 1a for the in vitro experimental design)
The peptides extended half-life (~68 days) supports weekly administration without significant loss of activity between doses [1]
Alternative (3/week): Consistent 2.0 mg per injection for simplified scheduling
and Juneau et al., the severity of endometriosis was not clarified, and without laparoscopic confirmation, the control groups may have included a number of patients with endometriosis
The incidence of gastrointestinal adverse events was 72.5% with CagriSema versus 34.4% with placebo, predominantly transient and mild to moderate in severity
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