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The Journal of The Association Genetic Technologists 33(2), 2007

Immune checkpoint inhibitors, such as anti-PD-1 and anti-CTLA-4, are designed to reactivate exhausted T cells and restore their cytotoxic function against tumor cells [9, 130, 167]

Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F

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Understanding its metabolism is crucial for safe dosing and recovery, as taking additional doses too soon or combining them with other medications can increase the risk of toxicity and liver damage