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doi: 10.3389/fphar.2025.1737199 Received 01 November 2025 Revised 21 December 2025 Accepted 29 December 2025 Published 15 January 2026 Volume 16 - 2025 Edited by Dawei Chen, University of Kiel, Germany Reviewed by Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Updates Copyright 2026 Knudsen, Tadje, Coggins and Venketaraman

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It's approved for adults with a BMI 30 kg/m or 27 kg/m with at least one weight-related comorbidity, as an adjunct to reduced-calorie diet and increased physical activity

Melatonin attenuated early brain injury induced by subarachnoid hemorrhage via regulating NLRP3 inflammasome and apoptosis signaling