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With any supplement, experts recommend starting small and working your way up to a higher dose

Front Endocrinol (Lausanne) 12: 785242, 2021

Additionally, the same detox and metabolism triggered by the above can also cause a partial histamine breakdown and trapping of methylhistamine which can aggravate all the Sx you mention as well

Important caveat: every claim above comes from cell-culture or animal studies of the individual peptides

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