OBrien S, Giles F, Rai K, Andreeff M , Cunningham C, Frankel S, Keating M
10.1177/039463200902200224 146 NiraulaA.SheridanJ
Patients should be advised to maintain consistent timing of levothyroxine administration and to report any symptoms suggestive of thyroid dysfunction, such as palpitations, tremor, anxiety (suggesting hyperthyroidism), or worsening fatigue and weight gain (suggesting hypothyroidism)
For women, particularly postmenopausal patients with increased cardiovascular risk, this low-dose regimen could serve as a preventive metabolic therapycomplementing hormone optimization, nutrition, and exercise to extend healthspan and protect against heart disease, the leading cause of death in women