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Pharmaceutical manufacturers need to do a lot of testing to get FDA approval
Kidney outcomes included a composite of 50% reduction in estimated glomerular filtration rate, kidney failure or death caused by kidney failure, and annualized rate of decline in estimated glomerular filtration rate (estimated glomerular filtration rate slope)
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Note that in some instances, doses higher than those used in the treatment of type 2 diabetes were chosen (for example, semaglutide 2.4 mg weekly injections)
The effect of lowering fasting glucose level and glycated hemoglobin is generally greater with long-acting agents, and the effect of lowering postprandial glucose level is more evident with short-acting agents
The effectiveness of GLP-1 injections in weight loss is due to their ability to influence several key processes in the body: 1
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