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In this population, Victoza is FDA approved to reduce the risk of major cardiovascular events, such as heart attack, stroke, and cardiovascular death, while Jardiance is FDA approved to specifically lower the risk of cardiovascular death

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According to a Cochrane analysis, although some beneficial effects on pain and improvement in vibration perception threshold have been reported, no conclusive evidence has been found to support a significant reduction in pain after 612 months of treatment with acetyl-L-carnitine in patients with DPN [111]

Gastrointestinal events were mild to moderate