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One possible scenario is the metabolic cofactor NADPH, which is known to be required not only for lipid synthesis but also for the function of antioxidant reductases, such as glutathione reductase (GSR) and thioredoxin reductase (TXNRD) 86

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In addition, simulations of the GSH adducts of TRaQ-G and MeTRaQ-G were performed following the protocol described above