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This applies to all GLP-1 therapy, not just Ivim Health

To ensure the efficacy of semaglutide for weight management, additional research was conducted, including the STEP (Semaglutide Treatment Effect in People with Obesity) clinical trial program

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In a meta-analysis of 10 placebo-controlled trials including over 71,000 subjects with or without diabetes at recruitment, treatment with SGLT2 inhibitors reduced the risk of heart failure hospitalization or cardiovascular death by 24% and lowered the risk of poor renal outcomes by 32% (Barbarawi 2021)

Skin lightening is a secondary effect caused by melanin suppression