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426 IF alone or combined with exercise is effective at lowering intrahepatic triglyceride (IHTG) levels and reducing hepatic steatosis in patients with NAFLD, possibly by downregulating hepatic inflammatory pathways, modifying lipogenic gene expression and increasing levels of autophagy

Studies have shown that the MLH1 protein, critical for regulating the MMR pathway, when under-expressed owing to hypermethylation of the hMLH1 gene promoter, resulted in decreased sensitivity in cancer cells

Iron, magnesium, selenium, and B-complex vitamins support enzymatic velocity and mitochondrial metabolic throughput [100]

Timing fiber intake, particularly soluble fiber, around meals can help to minimize postprandial glucose spikes by slowing down the absorption of glucose during digestion, leading to a more gradual rise in blood glucose and lasting feelings of satiety following meals

It is indirectly responsible for stimulating GLP-1 secretion and most known for strengthening gut integrity