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But cyanocobalamin is safer and more widely used

The hydroxylation of HIF-1 normally occurs continuously under normoxic conditions which stimulates ubiquitylation and proteasomal degradation of HIF-1, thereby restricting the transcription factor function of HIF-1

Deeks J, Higgins J, Altman D (2011) Chapter 9: Analysing data and undertaking meta-analyses

Patients often have serious medical comorbidities, i.e