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2 MetS and kidney diseases 2.1 The definition of MetS The concept of MetS was initially introduced by Grundy and colleagues in 2001 (17), which considerably arises from chronic inflammation caused by insulin resistance, along with disturbances in the metabolism of proteins, fats, carbohydrates, and other substances in the human body (18)
doi: 10.1080/10245332.2017.1318334
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52 In particular, butyrate can inhibit the production of proinflammatory cytokines, exert an anti-inflammatory effect, and affect BP by regulating the gut microbiota and the renin-angiotensin system
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