Yes, tretinoin is a first-line treatment for blackheads, whiteheads and comedonal acne
D P Jones, R J Coates, E W Flagg, J W Eley, G Block, R S Greenberg, E W Gunter, B Jackson - Glutathione in foods listed in the National Cancer Institute's Health Habits and History Food Frequency Questionnaire - Nutr Cancer - 1992
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In animal studies, its shown to increase blood flow to a given area through angiogenesis, or the formation of new capillaries
However, these findings are preliminary and need to be confirmed through rigorous clinical trials in humans