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By that same year, it had become one of the top 100 most-prescribed drugs in the US
More recently, a family of potent and highly selective mechanism-based suicide substrate inhibitors were developed and shown to promote the irreversible inhibition of gut microbiotadependent generation of TMA, suppression of host TMAO levels, and, in parallel, inhibition of platelet hyperresponsiveness and thrombosis potential in animal models (22)
This failure to warn argument is a common foundation in pharmaceutical litigation
Computational and Theoretical Chemistry , 1227, 114227
Shrestha YB et al
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