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Progress in spatial transcriptomics Recent advances in spatial transcriptomics have provided new insights into the molecular mechanisms of depression, allowing researchers to identify gene modules associated with depression-like behaviors at both the cellular and cortical levels

A reduced appetite can make it difficult to meet nutritional needs, especially if meals become very small

Acylcarnitines that accumulate through disordered carnitine metabolism directly inhibit the surface activity of pulmonary surfactants and are considered risk factors for increased lung injury due to a second hit, such as respiratory tract infection, sepsis, or inhalation of toxins, in patients with dysregulated FAO [304, 305]

Add obesity and insulin resistance, and that risk compounds

Premenopausal women tend to store fat in their lower bodies, while postmenopausal women and older men are more likely to store fat around their abdomen