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The increase in gastrointestinal problems has been well-documented, and the rise in low blood pressure and kidney stones is probably because GLP-1 patients could be somewhat fluid-depleted from not eating or drinking as much, said Dr Stephen ORahilly, co-director of the Institute of Metabolic Science at the University of Cambridge
Health Plant Sci
Changes in body composition with GLP-1 receptor agonists: A systematic review and meta-analysis
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For example, in the STEP-1 clinical trial, participants taking semaglutide lost an average of 11.6 pounds of lean body mass compared to just 4 pounds in the placebo group
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