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Li Z, Han Z, Sun R, Xuan X, Huang C
The full effect takes several months to develop, particularly at lower doses during the titration phase
That magnitude of weight loss, sustained over more than a year, transformed semaglutide from a diabetes medication into a proven medical weight-management tool
Just that one small subtle substitution, enhancing the molecular weight by 14 daltons, substantially increased the stability of the the peptide, says Paul Levine, a chemist at peptide company Insamo in California, US
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