Malavazos AE, Iacobellis G, Dozio E, Basilico S, Di Vincenzo A, Dubini C, et al
It is always best to prioritize safety and discard expired vials
Studies consistently show that weight regain begins soon after stopping medication and is proportional to the amount of weight originally lost: Semaglutide (Wegovy) : In the STEP 1 extension study, participants who lost an average of 17% of their body weight regained approximately two-thirds of that weight within one year of stopping the medication
Specifically, the relative abundance of Desulfobacterota doubled in the anterior region, while the levels of Firmicutes increased and Proteobacteria, Actinobacteriota, and Campylobacterota were reduced in the posterior region when supplementing the diet with bile salts (Ruiz et al., 2023)
These include: Gastrointestinal disturbances Skin reactions Allergic reactions These effects are usually mild and short-lived