Certainly, an increase in IGF-1 action is associated with greater risk for neoplastic disease, a link further supported by this study and others targeting IGF-1Rs, but IGF-1 has been paradoxically associated with protection against osteoporosis, type 2 diabetes, cerebrovascular and cognitive decline in pre-clinical studies, as well as in some human epidemiologic studies 12
The safety profile of retatrutide is consistent with that of other GLP-1-based agents
If one of them does get it quickly, we hedge the risk from the inevitable drop from Novo and Lilly
Both medications work best when combined with healthy nutrition, portion control, and regular physical activity
PCOS , or polycystic ovarian syndrome, is thought to impact 7-8% of women who are fertile