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Endogenous Roles The compound performs three main functions: neutralizing reactive oxygen species, conjugating xenobiotics for Phase II detoxification (via glutathione S-transferases), and recycling other antioxidants such as vitamins C and E

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The nonenzymatic initial reaction between 1 M roGFP2 WT (S 2 ) and physiological millimolar GSH concentrations was too slow to be detectable and to be of any relevance in the presence of glutaredoxins in accordance with previous analyses 32