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SURMOUNT-1 enrolled 2,539 adults with obesity or overweight with at least one weight-related complication
These dissolve in the mouth, delivering tirzepatide through the oral mucosa similar to drops but in a solid format
The 36 mg orforglipron tablet delivers approximately 28 mg of bioavailable drug, whereas the 14 mg Rybelsus tablet delivers roughly 0.06-0.14 mg of bioavailable semaglutide
Initial lab test: Not included and not usually required
Most commonly, you must either have type 2 diabetes or meet certain weight requirements - typically a BMI of 30 or higher, or a BMI of 27 or higher with at least one weight-related health condition (like high blood pressure or high cholesterol)
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