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GLP-1 medications, such as semaglutide in Ozempic/Wegovy and the newer GLP/GIP medication tirzepatide (Mounjaro/Zepbound), were originally developed to lower blood glucose in patients with type 2 diabetes

This is how they were studied in clinical trials, and we know that lifestyle modification remains the foundation of any chronic weight treatment. McGowan suggests working with a registered dietitian and personal trainer

Even people who do not lose [more than] 5% of weight seem to benefit from the treatment, she explains

OSA severity dropped substantially on average, but many patients still had residual disease combination therapy might be needed for optimal outcomes

Network meta-analyses help bridge this gap, but direct comparison data would be more definitive