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Transparent communication enables healthcare professionals to provide individualised advice, monitor for potential complications, and adjust treatment plans as necessary
With respect to the primary endpoint of A1C reduction from baseline, dulaglutide 4.5 mg was superior to the 1.5 mg dose at Week 36 under the treatment regimen estimand (mean change from baseline [mean baseline 8.6%]: dulaglutide 1.5 mg -1.54%, dulaglutide 4.5 mg -1.77%
Optimal results occur with consistent use over 3-6 months, as GHs effects are cumulative and require time for tissue remodeling
doi: 10.1152/ajpgi.00251.2007 50 ZhaoHZhuHLinZLinGLvG
In the genetic analysis, each genetically predicted 1 kg/m lower BMI through GLP-1R activation corresponded to approximately 18% lower odds of major depressive disorder and 39% lower odds of bipolar disorder
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