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This explanation is still a hypothesis from different papers, but it is consistent with how these medications act across different conditions

Animal studies have shown that GLP-1 agonists can dampen excessive HPA axis signaling, potentially reducing cortisol overproduction

Patient Adherence Injection Burden: Once-weekly dosing improves adherence, but oral formulations (under development) could further enhance compliance

Some patients start with GLP-1 medications, lose some weight, and then transition to surgery for more durable results

Weight loss journeys can be difficult, even when you are under different peptide therapy