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Human Biology and Health

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Having a closer look at the heat map illustrating the gene expression profile of PBMC, most of the genes showed massive changes in expression due to LPS injection, but were not affected by L-carnitine supplementation

Additionally, ROS activate the hypoxia-inducible factor-1 alpha (HIF-1) pathway, leading to increased expression of vascular endothelial growth factor (VEGF) and the formation of retinal neovascularization [186]

The samples were vortexed and incubated at 4 C for 1 h on a rotary shaker