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For someone struggling with life-altering low blood sugar this was really difficult

Unlike jumping straight to a therapeutic dose, the Retatrutide starting dose phase typically lasts four weeks

However, it is important to understand that this was a population at very high risk of renal and cardiovascular events, and the authors warn that the outcomes in this study may not be generalisable to other populations

Risk-of-bias assessment was done independently by two reviewers and any disagreements were resolved through consensus

Decrease dose if: Experiencing consistent side effects (headaches, fatigue, GI disturbance), achieving satisfactory results at current dose with no need for escalation, or cost considerations favor using minimum effective dose