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Fibroblasts are the cells responsible for synthesizing collagen and the extracellular matrix, which form the structural framework of all connective tissues

Emerging data from proteomics and genomic studies suggest that the development of super-resistant fungal strains is associated with critical genomic transitions (Burrack et al., 2022

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A study (60) found that polystyrene nanoplastics (PS-NPs) induced significant toxic effects on brain tissue cells in orange-spotted groupers ( Epinephelus coioides ), the mechanism involves significant downregulation of immune-related genes following PS-NP exposure, which accelerates viral replication and reduces cellular and tissue resistance to viral infection

Briefly, cells were sequentially treated with the medium containing 25 M of CldU (Sigma-Aldrich, C6891) and then 250 M of IdU (Sigma-Aldrich, I7125) for 20 min