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In particular, IL-1 and IL-6 are well recognized to contribute to oncogenesis and their expression is abundantly found in GBM cell lines and tissues (Lu et al., 2007
It was not until 6 months of age that both ferroptosis and apoptosis characteristics appeared simultaneously, confirming that ferroptosis occurs earlier than apoptosis in PD pathogenesis (190)
Unveiling the significance of the B12 daily dose for a comprehensive understanding of its benefits and potential drawbacks
it is required for the proper functioning of the enzyme gamma glutamyl transpeptidase (GGT) which is involved in the synthesis of glutathione [10]
Mechanistically, total intracellular iron alone is not the whole storyhow a tumor uses iron (for DNA repair, energy metabolism, redox buffering, etc.) and the cells lineage-specific biology determine whether ferritin acts mainly as a protective iron reservoir or as a regulator of metabolism and redox state [3, 88]
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