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Yamanaka factors A set of four transcription factors (MYC, KLF4, OCT3/4 and SOX2) that are highly expressed in embryonic stem cells
Understanding how to maximize value while maintaining protocol effectiveness helps justify the expense and avoid waste
This is a critical factor in the treatment of patients over 30 years of age
Impaired TrkB signaling underlies reduced BDNF-mediated trophic support of striatal neurons in the R6/2 mouse model of Huntingtons disease
Why this dose+ Reached in phase 2 by a different ladder: 0.6 mg start, doubling every 2 weeks (0.6 1.2 2.4 4.5)
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