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The mean BMI was approximately 25.8 kg/m2

Two different selenium-dependent iodothyronine deiodinases (DIOs type 1 and 2) can deiodinate T 4 , thus increasing circulating T 3 , while a third iodothyronine deiodinase (DIO type 3) can convert both T 3 and T 4 to inactive metabolites ( Figure 3 ) (10, 11)

[25] Higher SHBG concentrations reduce the proportion of free, biologically active oestrogen and testosterone in circulation, which can influence symptoms and physiological effects even when total hormone levels remain unchanged

Additionally, it aids in detoxifying the body from harmful chemicals and toxins, while influencing melanin synthesis to potentially enhance skin tone and complexion

This hormonal process makes the stomach empty slower and signals the brain that the body feels full reducing appetite and cravings, and over time leading to weight loss