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Conclusions The findings of this meta-analysis of seven RCTs (6609 participants) suggest a dose-dependent superiority of all three tirzepatide maintenance doses on glycaemic control, not only vs placebo but also vs long-acting GLP-1 RAs and basal insulin regimens
In addition to stimulated release in response to food intake, OXM exhibits diurnal variation in its concentration in the blood with highest levels detected in the evening and lowest levels in the morning
For this study, researchers analyzed the health data from a national database of more than 229,000 obese, non-diabetic people
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