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Mechanistically, auxin enhances TIR1-substrate affinity by acting as a molecular glue (Figure 4A)

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doi: 10.1182/blood.V126.23.3059.3059 Summary Keywords CLL - chronic lymphoblastic leukemia, BTK - Brutons tyrosine kinase, Bcl-2 inhibitor, Mcl-1 inhibitor, ibrutinib, venetoclax, glutamine (Gln) metabolism Citation Timofeeva N, Ayres ML, Baran N, Santiago-OFarrill JM, Bildik G, Lu Z, Konopleva M and Gandhi V (2023) Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia

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Li K, Mo W, Wu L, Wu X, Luo C, Xiao X, et al