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Standard GLP-1 eligibility thresholds - based on the FDA-approved drug labeling for Wegovy and Zepbound, which guides how clinicians think about the category - generally include a BMI of 30 or higher (obese), or a BMI of 27 or higher with at least one weight-related comorbidity such as high blood pressure, high cholesterol, or type 2 diabetes

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Diabetes (2008) 57(5):13408

Frequently asked questions How long does it take to reach the full 12mg retatrutide dose

A recent review of studies, led by Chen, found that older adults are more likely to experience these symptoms when taking these drugs