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The increased gallstone risk may be attributable to two mechanisms: the rapid and substantial weight loss these medications facilitate, and potentially direct effects of GLP-1 agonists on reducing gallbladder motility and emptying

14 in JAMA Ophthalmology, found semaglutide was "not associated with an increased risk of eye disorders." But the experts note the importance of more research, monitoring patients for any problems and paying attention to symptoms

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