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Research has focused on its interactions with collagen synthesis regulatory pathways in fibroblast cell line models, including TGF-beta signalling assays and matrix metalloproteinase (MMP) modulation studies

In fact, medical experts maintain that these treatments are generally safe and well-tolerated by most patients

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Following that, the discovery of bioactive peptides in the venom of arthropods and cephalopods changed the direction of research to identifying natural peptides from far-flung sources