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PubMed Central, doi:10.1002/ijc.28565

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Studies have shown that chronic hyperglycemic diets increase the risk of colon cancer, in part by regulating the insulin/IGF-1 signaling axis by activating the downstream PI3K/AKT/mTOR, Ras/MAPK signaling pathways, glucose transporter proteins (GLUT1) and key enzymes of glycolysis (LDHA and HK2), thereby affecting glucose uptake and aerobic glycolysis in cancer cells (65)

P = 0.0081

Of note, statin members that have been proven to inhibit NADPH oxidase enzymes are atorvastatin, fluvastatin, simvastatin, and rosuvastatin (Malfitano et al