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Death by 90 days occurred in 14.5% of patients in the seven-day group compared with 16.1% of patients in the 14-day group (difference, -1.6 percentage points

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These reactions are rare but serious

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We lose collagen and elastin in the deep tissues

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Protocol details: Initial phase dose: 20-30 ml per day Initial phase route: IV infusion (diluted in 100-250 ml saline) Initial duration: 14-21 days Maintenance dose: 10 ml per day Maintenance duration: 14 additional days Infusion time: 30-60 minutes (never rapid bolus at these doses) Expected timeline based on TBI trial data: Day 7-10: Improved neurological scores on GCS Day 21: Favorable GCS in treated patients with contusion and diffuse axonal injury Week 12: Significant cognitive improvement (CASI scores) in mild TBI Month 6: 67% achieved good outcomes (GOS 3-5) in moderate to severe cases Protocol 3: combination approach with donepezil Goal: Maximize cognitive benefit in established dementia through complementary mechanisms

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While glutathione is approved for certain medical applications, its use for cosmetic enhancement remains off-label, placing responsibility on providers and patients to navigate potential risks without regulatory guidance

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