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48 NovkK.PeinaK.NebesovJ.krdletaV.LisL.NainecV
T., Morton P
Systematic Literature Search A comprehensive literature search was conducted in the Cochrane Library database to identify relevant RCTs with semaglutide and cardiovascular outcomes as the primary endpoints
Researchers at the University of Halle demonstrated that H89, a PKA inhibitor, could block retatrutide chronotropic effects but not those of isoprenaline (a beta-adrenergic agonist), confirming that retatrutide works through a distinct PKA-dependent mechanism rather than through the sympathetic nervous system
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